The Center draws upon the expertise of a wide range of investigators with complementary interests in diabetes, obesity, inflammation, lipid metabolism and atherosclerosis. Members of the Center’s faculty conduct both basic research to clarify the mechanisms causing diabetes and obesity and their consequences, and translational research to transform their research findings into clinical solutions.
Two-thirds of the adult U.S. population is overweight and one-half of those individuals – one-third of the adult population – are obese. The prevalence of type 2 diabetes (formerly known as “adult-onset”) has also increased markedly in recent decades not only among adults, but in children as well. Although type 1 diabetes is less common, it is a potentially devastating disorder affecting both children and adults and, while treatments for both types of diabetes exist, neither is curable and effective treatments for obesity have yet to be developed.
Much of the good we accomplish is made possible by private support: by people and organizations underwriting leading-edge research and providing funding to train promising fellows. With your help, the DOCE is improving lives throughout the Northwest and around the world.
The seminar series features lectures from nationally recognized experts from across the country, and on occasion from overseas. Click here to learn more and to see the calendar of upcoming lectures.
Dr. Laura den Hartigh has been awarded an NIH K01 to examine the mechanisms by which 10,12CLA confers resistance to diet-induced weight gain in mice.
Dr. Karin Bornfeldt is the recipient of a Pilot and Feasibility award from the NIDDK-sponsored Diabetic Complications Consortium for her project ‘Diabetes and miRNA’.
Dr. Ian Sweet is the recipient of the 2013 Gail Patrick Innovation Award from the ADA. This award is granted to Innovation award applications to the ADA that receive the highest priority score.
Dr. Joshua Thaler is the 2013 recipient of the Fialkow Award. The Fialkow Award is awarded annually to recognize the outstanding achievements of junior faculty in medicine in research, teaching, clinical work, and academic citizenship.
Dr. Joshua Thaler has been selected as the recipient of a 2013 Early Investigators Award by The Endocrine Society. The Early Investigators Awards provide monetary support to assist in the development of early career investigators and recognition of their accomplishments in endocrine research.
DOCE Director Michael W. Schwartz, MD (MTE) is senior author of a paper published in the Journal of Clinical Investigation that presents the first evidence of structural change in the brain in both rodents and humans associated with diet-induced obesity. DOCE researcher Dr. Josh Thaler, MD, PhD, (MTE), is the first author on the paper entitled ʽObesity Is Associated with Hypothalamic Injury in Rodents and Humansʼ which was published in the January 3rd issue.
Dr. Jay Heinecke, MD (MTE) has been awarded an NIH/NHLBI R01 for his project entitled “Quantitative Assessment of HDL Function”. The goal of the research is to identify proteins that alter HDL’s function and are selectively enriched or depleted in subjects at risk for CVD.